We started the year with one, so let's end the year with one (and as it's nice, let's do it twice) *Taken from the NEJM Image Challenge* A 60-year-old man presented to the hematology clinic with fatigue and dyspnea on exertion. He had a history of sickle cell disease with hemoglobin genotype SS. Laboratory studies showed a hemoglobin level of 4 g per deciliter. Light microscopy of a bone marrow biopsy specimen is as shown. What is the diagnosis? Sideroblastic anemia B-cell acute lymphoblastic leukemia Aplastic anemia Hemophagocytosis of sickle cells Multiple myeloma Comment below with your answer!
